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Necrosis
Necrosis is the term that describes the premature death of skin cells caused by disease or infection. Unlike apoptosis, which is the natural and normal cycle of cell death, necrosis is caused by unnatural factors. For example, a bite from the brown recluse spider can cause severe and sometimes fatal necrosis of the skin, as the venom attacks the skin cells, killing them in the process. Other factors, such as a blockage of blood flow to the muscles may cause necrosis. Surgery and certain medications can be used to prevent necrosis from spreading or destroying the ability for certain organs to function.